What to Know About Refrigerating Supplements

Which supplements belong in the fridge, and which can be stored in a cupboard or closet?

One of the most common questions is where supplements should be stored. With so many formats and formulas, it can be hard to know what’s best. 

You might be wondering…

  • Should all probiotics be refrigerated?
  • Do softgels need to stay cold so they don’t stick together?
  • Are powders fine in a cupboard, or do they need refrigeration?
  • What about liquid and gummy supplements?

Here’s a simple guide to help you store your supplements properly and get the most out of every dose.

General rules for storing supplements

When in doubt, check the label! Storage directions listed on the label are always your best source of truth and may vary by formula.

Unless otherwise noted, most supplements should be stored in a climate controlled environment:

  • Cool
  • Dry (low humidity)
  • Away from direct sunlight

Following these guidelines helps maintain potency, stability, and product quality.

Probiotics

Many probiotics do require refrigeration, but not all. 

  • Refrigerated probiotics: Some strains are sensitive to heat and need cold storage to maintain potency. If your probiotic requires refrigeration, get it into the fridge as soon as possible! For instance, our Primadophilus® Reuteri Probiotics must be kept refrigerated to maintain maximum potency.
  • Shelf stable probiotics: These are designed to maintain potency at room temperature and can be stored in a cabinet or pantry. For example, our Pearls Probiotics® do not need refrigeration.

Always check the label to confirm where you should store your probiotics.

Liquids and syrups

Liquid and syrup supplements vary when it comes to storage:

If you’re unsure whether a liquid supplement is still fresh, expiration date guidance can help you decide whether it’s time to replace it.

Powders

Moisture is the biggest enemy here, so keep lids tightly closed and avoid storing near heat or steam.

Softgels and gummies

Softgels and gummies do not require refrigeration, but they are sensitive to heat and humidity. Store them in a cool, dark, and dry place. Try to avoid bathrooms, which tend to be warm and humid.

If gummies or softgels stick together, don’t panic. Clumping does not affect potency or quality. Simply move them to a cooler location and they should separate over time.

Coconut oil, MCT oil, and flax oil 

Most coconut oil, MCT oil, and flax oil don’t need refrigeration and can be kept at room temperature. Coconut oil may shift between solid and liquid depending on temperature, but this is completely normal and does not affect its quality. As always, follow any specific storage instructions on the label.

Omega-3 and fish oil

Many liquid fish oil and omega-3 supplements require refrigeration after opening, like our Fish Oil Omega-3. Some softgels require refrigeration, but some do not. Check the label for guidance, then store accordingly to keep your omega-3s fresh.

The bottom line

Proper storage helps ensure your supplements stay potent and enjoyable to take. When you’re unsure:

  1. Read the label.
  2. Store supplements in a cool, dry, climate controlled space.
  3. Refrigerate when directions recommend it.

A little attention to storage goes a long way in supporting your wellness routine!