










Product information
Cortisol Manager®

SUPPORTS BALANCED CORTISOL & HEALTHY STRESS RESPONSE*
Cortisol is a hormone produced in the adrenal cortex that is released during times of stress. Variations in cortisol secretion can indicate how well the body is coping with stress. Cortisol Manager is a supplement that contains a stress-reducing proprietary blend of ingredients including Sensoril ashwagandha (Withania somnifera) and Suntheanine L-theanine to help support a balanced, adaptive cortisol response to stress.* The ingredients in Cortisol Manager help support relaxation and promote calm to support restful sleep.* They also help stabilize the stress hormone cortisol to support a healthy stress response.* Cortisol Manager is melatonin-free.

SUPPORTS BALANCED CORTISOL & HEALTHY STRESS RESPONSE*
Cortisol is a hormone produced in the adrenal cortex that is released during times of stress. Variations in cortisol secretion can indicate how well the body is coping with stress. Cortisol Manager is a supplement that contains a stress-reducing proprietary blend of ingredients including Sensoril ashwagandha (Withania somnifera) and Suntheanine L-theanine to help support a balanced, adaptive cortisol response to stress.* The ingredients in Cortisol Manager help support relaxation and promote calm to support restful sleep.* They also help stabilize the stress hormone cortisol to support a healthy stress response.* Cortisol Manager is melatonin-free.
CONFIDENCE IS HEALTHY
Confidence is healthy. At Integrative Therapeutics®, we empower individuals with supplements, experts, and resources that help them choose their best path to well-being in the confusing and complex world of health care. Our products are curated by clinicians, made with premium ingredients, and backed by science – and we’re here to support you on your journey.


CONFIDENCE IS HEALTHY
Confidence is healthy. At Integrative Therapeutics®, we empower individuals with supplements, experts, and resources that help them choose their best path to well-being in the confusing and complex world of health care. Our products are curated by clinicians, made with premium ingredients, and backed by science – and we’re here to support you on your journey.
5
Calories
1g
Total Carbohydrate
10mg
Sodium
500mg
Stress-Reducing Proprietary Blend: ashwagandha (Withania somnifera) (Sensoril® brand) root and leaf extract, L-theanine (Suntheanine®)
450mg
Cortisol-Reducing Proprietary Blend: magnolia (Magnolia officinalis) bark extract standardized to contain 2% honokiol and 1% magnolol, epimedium (Epimedium spp.) aerial parts extract
100mg
Phosphatidylserine (from soybean lecithin)
** Daily Value (DV) not established
†Percent daily value is based on a 2000 calorie diet
Cortisol Manager® Does Not Contain
Gluten
Dairy
Wheat
Other Details
Sensoril® is a registered trademark of Natreon, Inc. and is protected under U.S. Patent No. 7,318,938.
Suntheanine®, a patented form of L-Theanine, is a registered trademark of Taiyo International, Inc.
UPC: 871791003811
SKU: 70453
Cortisol Manager® Directions and/or Dosage
Adults, take 1 tablet before bedtime or as recommended by a healthcare professional. Increase to 2 tablets during times of high stress. For nightly use.Warning
Do not use if you are pregnant. If nursing, diabetic, or taking prescription drugs, consult a healthcare professional before use. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.While some individuals do take Cortisol Manager® during the day, caution should be used as it will cause you to relax and drowsiness may occur.†
While the ingredients do have a modulating effect, the small scale study shows a rather significant reduction in cortisol levels. Therefore, we would not recommend Cortisol Manager® for someone with low cortisol.
The source of the phosphatidylserine in Cortisol Manager® is vegetable glycerin. The glycerin, in turn, is derived from a highly purified, refined soybean oil, which contains no allergenic proteins.
Yes. Cortisol Manager contains phosphatidylserine sourced from soy. If your patients require a non-soy formula, you may want to consider standalone soy-free phosphatidylserine.
Though typically used within the early-stage of the stress response, Cortisol Manager can be used in the mid and late stages – particularly within the mid-stage when additional energy and stress support is needed.* The HPA Optimization program highlights key nutrient support that is appropriate for the mid and late stages, such as the adaptogenic herbal combination of HPA Adapt, for mid-stage, and CortiVive for late stage, which supports healthy cortisol production and healthy adrenal cortex function.
No, not when used properly. Research has shown that ashwagandha offers safe and effective support for the body during times of stress.* Unfortunately, there are some sources indicating that all plants of the Solanaceae or nightshade family (potatoes, tomatoes, peppers, eggplant, and ashwagandha, included) should be avoided because of their potential to reduce immune system function. However, many of these same plants and herbs have been used as food staples and medicines for thousands of years. These compounds, found in green part of the vegetables, may cause adverse effects in humans when taken at unrealistically high levels.
Cortisol Manager®

SUPPORTS BALANCED CORTISOL & HEALTHY STRESS RESPONSE*
Cortisol is a hormone produced in the adrenal cortex that is released during times of stress. Variations in cortisol secretion can indicate how well the body is coping with stress. Cortisol Manager is a supplement that contains a stress-reducing proprietary blend of ingredients including Sensoril ashwagandha (Withania somnifera) and Suntheanine L-theanine to help support a balanced, adaptive cortisol response to stress.* The ingredients in Cortisol Manager help support relaxation and promote calm to support restful sleep.* They also help stabilize the stress hormone cortisol to support a healthy stress response.* Cortisol Manager is melatonin-free.

SUPPORTS BALANCED CORTISOL & HEALTHY STRESS RESPONSE*
Cortisol is a hormone produced in the adrenal cortex that is released during times of stress. Variations in cortisol secretion can indicate how well the body is coping with stress. Cortisol Manager is a supplement that contains a stress-reducing proprietary blend of ingredients including Sensoril ashwagandha (Withania somnifera) and Suntheanine L-theanine to help support a balanced, adaptive cortisol response to stress.* The ingredients in Cortisol Manager help support relaxation and promote calm to support restful sleep.* They also help stabilize the stress hormone cortisol to support a healthy stress response.* Cortisol Manager is melatonin-free.
CONFIDENCE IS HEALTHY
Confidence is healthy. At Integrative Therapeutics®, we empower individuals with supplements, experts, and resources that help them choose their best path to well-being in the confusing and complex world of health care. Our products are curated by clinicians, made with premium ingredients, and backed by science – and we’re here to support you on your journey.


CONFIDENCE IS HEALTHY
Confidence is healthy. At Integrative Therapeutics®, we empower individuals with supplements, experts, and resources that help them choose their best path to well-being in the confusing and complex world of health care. Our products are curated by clinicians, made with premium ingredients, and backed by science – and we’re here to support you on your journey.
Learn About Our Quality Standards
5
Calories
1g
Total Carbohydrate
10mg
Sodium
500mg
Stress-Reducing Proprietary Blend: ashwagandha (Withania somnifera) (Sensoril® brand) root and leaf extract, L-theanine (Suntheanine®)
450mg
Cortisol-Reducing Proprietary Blend: magnolia (Magnolia officinalis) bark extract standardized to contain 2% honokiol and 1% magnolol, epimedium (Epimedium spp.) aerial parts extract
100mg
Phosphatidylserine (from soybean lecithin)
** Daily Value (DV) not established
†Percent daily value is based on a 2000 calorie diet
Cortisol Manager® Does Not Contain
Gluten
Dairy
Wheat
Other Details
Sensoril® is a registered trademark of Natreon, Inc. and is protected under U.S. Patent No. 7,318,938.
Suntheanine®, a patented form of L-Theanine, is a registered trademark of Taiyo International, Inc.
UPC: 871791003811
SKU: 70453
Cortisol Manager® Directions and/or Dosage
Adults, take 1 tablet before bedtime or as recommended by a healthcare professional. Increase to 2 tablets during times of high stress. For nightly use.Warning
Do not use if you are pregnant. If nursing, diabetic, or taking prescription drugs, consult a healthcare professional before use. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.While some individuals do take Cortisol Manager® during the day, caution should be used as it will cause you to relax and drowsiness may occur.†
While the ingredients do have a modulating effect, the small scale study shows a rather significant reduction in cortisol levels. Therefore, we would not recommend Cortisol Manager® for someone with low cortisol.
The source of the phosphatidylserine in Cortisol Manager® is vegetable glycerin. The glycerin, in turn, is derived from a highly purified, refined soybean oil, which contains no allergenic proteins.
Yes. Cortisol Manager contains phosphatidylserine sourced from soy. If your patients require a non-soy formula, you may want to consider standalone soy-free phosphatidylserine.
Though typically used within the early-stage of the stress response, Cortisol Manager can be used in the mid and late stages – particularly within the mid-stage when additional energy and stress support is needed.* The HPA Optimization program highlights key nutrient support that is appropriate for the mid and late stages, such as the adaptogenic herbal combination of HPA Adapt, for mid-stage, and CortiVive for late stage, which supports healthy cortisol production and healthy adrenal cortex function.
No, not when used properly. Research has shown that ashwagandha offers safe and effective support for the body during times of stress.* Unfortunately, there are some sources indicating that all plants of the Solanaceae or nightshade family (potatoes, tomatoes, peppers, eggplant, and ashwagandha, included) should be avoided because of their potential to reduce immune system function. However, many of these same plants and herbs have been used as food staples and medicines for thousands of years. These compounds, found in green part of the vegetables, may cause adverse effects in humans when taken at unrealistically high levels.
Learn About Our Quality Standards
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.